[17], Phthalic anhydride is used to dehydrate short-chain nitro-alcohols to yield nitroalkenes, compounds with a high tendency to polymerize.[18]. It is the anhydride of phthalic acid. Balaji Santhanam. This reaction is expected to be slow, but can become vigorous if local heating accelerates it. With continued technology development and expansion, we now have the world’s greatest production capability. Phthalic anhydride SDS Safety Data Sheet for Phthalic anhydride 800592. Phthalic acid is an aromatic dicarboxylic acid, with formula C 6 H 4 (CO 2 H) 2.It is an isomer of isophthalic acid and terephthalic acid.Although phthalic acid is of modest commercial importance, the closely related derivative phthalic anhydride is a commodity chemical produced on a large scale. Inhalation Remove to fresh air. Vapor pressure is < 0.3 Pa at 20 ° C. In presence of water phthalic anhydride hydrolyzes to phthalic acid. Chiral alcohols form half-esters (see above), and these derivatives are often resolvable because they form diastereomeric salts with chiral amines such as brucine. PA is soluble in alcohol and carbon disulphide. Reaction with water is accelerated by acids. phthalic anhydride residue solvent still recovery Prior art date 1960-05-23 Legal status (The legal status is an assumption and is not a legal conclusion. : 85-44-9 MSDS SECTION 1: Identification of the substance/mixture and of the company/undertaking Above 180 °C, phthalic anhydride re-forms. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) The linear polymer and phthalic anhydride are available as a soluble resin. Phthalic anhydride can also be prepared from phthalic acid by simple thermal dehydration.[4]. Above 180 °C, phthalic anhydride re-forms. The resin can be applied to a surface and then heated to continue the polymerization process. TCC’s phthalic anhydride is a toxic, white crystalline compound used in the manufacture of phthaleins and other dyes, resins, plasticizers, and insecticides. Phone : + 91 - 04172 - 244441 / 244442 / 244446 Fax : + 91 - … It may be prepared by adding a hot solution of phthalimide to a solution of potassium hydroxide; the desired product precipitates. Phthalic anhydride is widely used in organic syntheses for the manu- Encyclopedia of Reagents for Organic Synthesis. Phthalate esters are derived from phthalic anhydride by the alcoholysis reaction. NACRES NA.21 Molecular Weight 148.12 . Logistics services are available in the United States. Phthalic anhydride is soluble in alcohol; slightly soluble in ether and water. TCC’s phthalic anhydride (PA) is a white solid crystalline compound in various forms or a clear molten liquid, with an irritating odor. Varma, V.B. Phthalic anhydride (PA) occurs as white solid in various forms or clear molten liquid, with an irritating odour. Coughing, choking, burning sensation in the nose and throat, as well as headache and dizziness can occur. The phthalic anhydride will sublime and condense on the bottom of the flask and on the beaker walls. Phthalic anhydride is a common laboratory chemical, Pthalic anhydride has been shown to be esterified with primary alcohols at room temperature. SDS / MSDS Product Name: PHTHALIC ANHYDRIDE Revision Date : 03.06.2019 Page 1 of 6 1. Search for more papers by this author. The solubility of phthalic anhydride was measured at 283–313 K under atmospheric pressure in ethyl acetate, n -propyl acetate, methyl acetate, acetone, 1,4-dioxane, n -hexane, n -butyl acetate, cyclohexane, and dichloromethane. 1989]. Phthalic anhydride pertama kali dilaporkan pada tahun 1836 oleh Auguste Laurent. Phthalic anhydride is a versatile intermediate in organic chemistry, in part because it is bifunctional and cheaply available. Encyclopedia of Reagents for Organic Synthesis. ... Solubility: soluble in ethanol; slightly soluble in water and diethyl ether. The phthalic acid is somewhat soluble in water. Eyes: Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. Phthalic anhydride is an important chemical intermediate in the plastics industry from which are derived numerous phthalate esters that function as plasticizers in synthetic resins. Hydrolysis of anhydrides is not typically a reversible process. The modern industrial variant process instead uses vanadium pentoxide (V2O5) as the catalyst in a gas-phase reaction with naphthalene using molecular oxygen. 2.01.2.2.2 Anhydrides. The phthalic acid is somewhat soluble in water. Phthalic anhydride is also used as a precursor of anthraquinone, phthalein, rhodamine, phthalocyanine, fluorescein, and xanthene dyes. Early procedures involved liquid-phase mercury-catalyzed oxidation of naphthalene. Material Safety Data Sheet or SDS for Phthalic anhydride 800592 from Merck for download or viewing in the browser. Phthalic Anhydride (PA) is used as the major ingredient in the manufacture of plasticizers, unsaturated polyester resin, paint and others. First Aid Measures Inhalation: MAY BE FATAL IF INHALED. Phthalic anhydride itself is used as a monomer for synthetic resins such as glyptal, the alkyd resins, and the polyester resins. Phthalic anhydride is the anhydride of phthalic acid. Phthalic anhydride has another major use in the production of polyester resins and other minor uses in the production of alkyd resins used in paints and lacquers, certain guys, insect repellents, and urethane polyester polyols. It was discovered in 1871 by Adolf von Baeyer. Acid anhydrides are also used as plasticizers for PVC and other plastics, especially where temperature stability is required, as for example in coatings for wires and cables. Hydrolysis of anhydrides is not typically a reversible process. Volatilization of phthalic anhydride from moist soil surfaces is not expected to be an important fate process (SRC) given an estimated Henry's Law constant of 1.7X10-8 atm-cu m/mole (SRC) based upon its vapor pressure, 5.17X10-4 mm Hg (5), and water solubility, 6000 mg/L (6). Phthalic anhydride reacts violently with CuO at elevated temperatures [Park, Chang-Man, Richard J. Sheehan. C 6 H 4 (CO) 2 O + H 2 O → C 6 H 4 (CO 2 H) 2. A well-known application of this reactivity is the preparation of the anthroquinone dye quinizarin by reaction with para-chlorophenol followed by hydrolysis of the chloride. Phthalic anhydride is a principal commercial form of phthalic acid. Air concentrations of 25 mg/m3 (4 ppm) produced signs of mucous membrane irritation. It was the first anhydride of a dicarboxylic acid to be used commercially. Phthalic anhydride is the organic compound with the formula :-C6H4(CO)2O. Geert‐Jan Boons. Other reactions with phthalic anhydride yield phenolphthalein, benzoic acid, phthalylsulfathiazole (an intestinal antimicrobial agent), and orthophthalic acid. EC Number 201-607-5. InChI=1S/C8H4O3/c9-7-5-3-1-2-4-6(5)8(10)11-7/h1-4H, Except where otherwise noted, data are given for materials in their, National Institute for Occupational Safety and Health, Ullmann's Encyclopedia of Industrial Chemistry, "Development of a gel permeation chromatographic assay to achieve mass balance in cellulose acetate phthalate stability studies", https://en.wikipedia.org/w/index.php?title=Phthalic_anhydride&oldid=998651643, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Creative Commons Attribution-ShareAlike License, This page was last edited on 6 January 2021, at 11:24. [4] In the 1980s, approximately 6.5×109 kg of these esters were produced annually, and the scale of production was increasing each year, all from phthalic anhydride. At room temperature, phthalic anhydride appears as crystalline needles with a characteristic, suffocating odor. Synonym: 1,3-Isobenzofurandione It was the first anhydride of a dicarboxylic acid to be used commercially. MATERIAL SAFETY DATA SHEET (MSDS) www.lobachemie.com 17/01/2019 1/11 PHTHALIC ANHYDRIDE FOR SYNTHESIS MSDS CAS-No. Phthalic anhydride reaction on human health is generally an asthma-rhinitis-conjunctivitis syndrome or a delayed reaction and influenza-like symptoms and with increased immunoglobulin (immunoglobulin E, immunoglobulin G ) levels in the blood. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a Phthalic anhydride is the organic compound with the formula C6H4(CO)2O. It is slightly soluble in hot water, hydrolysing to Phthalic Acid. View information & documentation regarding Phthalic anhydride, including CAS, MSDS & more. Phthalic anhydride has also been used as a rubber scorch inhibitor and retarder. Search for more papers by this author. [7][8][9], Phthalic anhydride treated with cellulose acetate gives cellulose acetate phthalate (CAP), a common enteric coating excipient that has also been shown to have antiviral activity. [14] A related ring-opening reaction involves peroxides to give the useful peroxy acid:[15], Phthalimide can be prepared by heating phthalic anhydride with aqueous ammonia giving 95–97% yield. It can also be produced by ammoxidation of o-xylene. Vapor pressure is < 0.3 Pa at 20 ° C. In presence of water phthalic anhydride hydrolyzes to phthalic acid. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a An alternative process involves oxidation of the two methyl groups of o-xylene, a more atom-economical process. University of Georgia, Athens, GA 30602. 1.3 Details of the supplier of the safety data sheet Company : Central Drug House (P) Ltd 7/28 Vardaan House New Delhi-10002 INDIA Manufacturer and Substance Identification Thirumalai Chemicals Limited, 25 - A SIPCOT Industrial Complex, Ranipet, 632403.Tamil Nadu, India. [11] Phthalic anhydride is a degradation product of CAP.[12]. [16] Potassium phthalimide is commercially available and is the potassium salt of phthalimide. Above 180 °C, phthalic anhydride re-forms. Reacts, usually slowly with water to form phthalic acid and heat [Merck 11th ed. University of Georgia, Athens, GA 30602. [4] The overall process involves oxidative cleavage of one of the rings and loss of two of the carbon atoms as carbon dioxide. Availability. Phthalic anhydride vapour, fume or dust is a primary irritant. PubChem Substance ID 24859242. Skin: Wash off with soap and plenty of water. In 2000, the worldwide production volume was estimated to be about 3 million tonnes per year.[4]. Our PA Plant is a manufacturing plant which opened for the first time in the Republic of Korea. Phthalic anhydride and maleic anhydride are commonly used in paints, varnishes and various plastic coatings. It is both an irritant and sensitizer of the skin and respiratory tract, and may produce asthma on repeated exposure. Gupta, in Comprehensive Composite Materials, 2000. This colourless solid is an important industrial chemical, especially for the large-scale production of plasticizers for plastics. Phthalic anhydride was first reported in 1836 by Auguste Laurent. PHTHALIC ANHYDRIDE: ICSC: 0315: 1,2-Benzenedicarboxylic acid anhydride Phthalic acid anhydride 1,3-Isobenzofurandione: June 2003 Phthalic anhydride is very slightly soluble in H2O, soluble in alcohol, and slightly soluble in ether. Phthalic acid is however easily dehydrated to form phthalic anhydride. Physical properties Colorless to pale cream crystals with a characteristic, choking odor. Product name : Phthalic Anhydride CAS-No. Empirical Formula (Hill Notation) C 8 H 4 O 3. Phthalic acid is very soluble in boiling water, 18 g/100 mL, and is much less soluble in chilled (14°C) water, 0.54 g/100 mL. Phthalic Anhydride. 100% Phthalic Anhydride 85‐44‐9 4. It is the anhydride of phthalic acid. EPA has determined that phthalic anhydride is a The process begins with the reaction of phthalic anhydride with alcohols, giving the monoesters: The second esterification is more difficult and requires removal of water: The most important diester is bis(2-ethylhexyl) phthalate ("DEHP"), used in the manufacture of polyvinyl chloride compounds. Phthalic anhydride is a versatile intermediate in organic chemistry, in part because it is bifunctional and cheaply available. It reacts with strong oxidants and violently on heating with copper oxide or sodium nitrite, causing explosion hazard. The most probable human exposure to phthalic anhydride is through skin contact or inhalation during manufacture or use. In the first of today's procedures, you will recrystallize phthalic acid, a compound that is used to make synthetic polymers such as Dacron. Geert‐Jan Boons. Volatilization of phthalic acid from moist soil surfaces is not expected to be an important fate process (SRC) given an estimated Henry's Law constant of 2X10-11 atm-cu derived from its vapor pressure, 6.36X10-7 mm Hg (3), and water solubility, 6965 mg/L (4). If breathing is difficult, give oxygen. MDL number MFCD00005918. Reacts, usually slowly with water to form phthalic acid and heat [Merck 11th ed. Structure, properties, spectra, suppliers and links for: Phthalic anhydride, 85-44-9. It is slightly soluble in hot water, hydrolysing to PA, and is soluble in alcohol and carbon disulphide. If breathing is difficult, give oxygen. Get medical attention. Phthalic acid is however easily dehydrated to form phthalic anhydride. Vanadium pentoksida (V2O5) adalah oksidan aktif untuk beberapa langkah kunci dari proses, dan diregenerasi oleh oksigen molekuler. Sigma-Aldrich offers a number of Phthalic anhydride products. This colorless solid is an important industrial chemical, especially for the large–scale production of plasticizers for plastics. +Add Attachment ... Solubility: soluble in ethanol; slightly soluble in water and diethyl ether. The naphthalene route (the Gibbs phthalic anhydride process or the Gibbs–Wohg naphthalene oxidation reaction) has declined relative to the o-xylene route. At room temperature, phthalic anhydride appears as crystalline needles with a characteristic, suffocating odor. John Wiley & Sons, Inc. 2005]. Get medical attention. Expired - Lifetime Application number US31013A Inventor Metro D Kulik Rute yang lebih kontemporer termasuk oksidasi naftalena atau orto-xilena. Phthalic anhydride ACS reagent, ≥99% CAS Number 85-44-9. Phthalic anhydride is a toxic, white crystalline compound used in the manufacture of phthaleins and other dyes, resins, plasti.... (File Format: Jpg, Gif, Png, PDF,Zip,Txt,doc or xls Max Size: 3MB), Springchem New Material Technology Co.,Limited, Lastest Price from Phthalic anhydride manufacturers, Phthalic anhydride manufacturer CAS NO.85-44-9 CAS NO.85-44-9, 2',7'-dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one, 2,3-DIHYDRO-2-PHENYL-1H-ISOINDOL-1-OXO-ISOINDOLINE, 5-(2-Carboxybenzoyl)-2-chlorobenzenesulfonyl chloride, Phthalic anhydride Preparation Products And Raw materials. Inhalation Remove to fresh air. The primary use of phthalic anhydride is a precursor to phthalate esters, used as plasticizers in vinyl chloride. (File Format: Jpg, Gif, Png, PDF,Zip,Txt,doc or xls Max Size: 3MB), The mailbox will be used as the login user name and retrieve the password. Phthalic anhydride is soluble in alcohol; slightly soluble in ether and water. Incompatible with acids, strong oxidizing agents, alcohols, amines, and bases. Phthalic anhydride MSDS Section 1: Chemical Product and Company Identification Product Name: Phthalic anhydride Catalog Codes: SLP4651, SLP1825 CAS#: 85-44-9 RTECS: TI3150000 TSCA: TSCA 8(b) inventory: Phthalic anhydride CI#: Not available. Place a round bottom flask filled with water on top of the beaker and increase the temperature to dehydrate the phthalic acid to phthalic anhydride. Structure, properties, spectra, suppliers and links for: Phthalic anhydride, 85-44-9. Balaji Santhanam. It is a principal commercial form of phthalic acid. If breathed in, move person into fresh air. If not breathing give artificial respiration consult a physician. TETRABROMOPHTHALIC ANHYDRIDE reacts exothermically with water. Liver and kidney injury occurred. Phthalic Anhydride (PA) White scaly or Crystalline powder, Molecular formula C8H403, Molecular weight 148.12, Melting point 131.1l , Boiling point 284.5 , Flash point 151 (close), 165 (open), Spontaneous combustion point 584 , Density (Solid) 1.527g / cm3, insoluble in water, soluble in water, alcohol, ether, benzene and most organic solvents. Copyright © 2017 ChemicalBook All rights reserved. Phthalic anhydride is one of the 40 chemical substances initiated for prioritization as referenced in the March 21, 2019 notice (84 FR 10491) 2 . It is the anhydride of phthalic acid. Alternatively, it may be prepared by treating the anhydride with ammonium carbonate or urea. 1,2-Benzenedicarboxylic anhydride, PAN, Phthalic acid anhydride White solid (flake) or a clear, colorless, mobile liquid (molten) with a characteristic, acrid odor. Hydrolysis of anhydrides is not typically a reversible process. Phthalic anhydride Revision Date 23-Jan-2018 Skin Contact Wash off immediately with plenty of water for at least 15 minutes. Phthalic Anhydride. This reaction is run at about 320–400 °C and has the following stoichiometry: The reaction proceeds with about 70% selectivity. The solubility of phthalic anhydride in … Cats repeatedly exposed to 3700 mg/m 3 of phthalic anhydride became drowsy, lost appetite and vomited. This white solid is an important industrial chemical, especially for the large-scale production of plasticizers for plastics. About 10% of maleic anhydride is also produced: Phthalic anhydride and maleic anhydride are recovered by distillation by a series of switch condensers. Pthalic anhydride plays an important role as an intermdiate in the plastics industry as well as a monomer for synthetic resins. Phthalic acid is however easily dehydrated to form phthalic anhydride. Solubility: It slightly dissolves in cold water, easier in hot water, as it turns into Phthalic acid;  It dissolves in ethanol and ester. Studies show that exposure to phthalic anhydride can cause rhinitis, chronic bronchitis, and asthma. Hydrolysis by hot water forms ortho-phthalic acid:[13]. Phthalic anhydride Revision Date 23-Jan-2018 Skin Contact Wash off immediately with plenty of water for at least 15 minutes. [6] Phenolphthalein can be synthesized by the condensation of phthalic anhydride with two equivalents of phenol under acidic conditions (hence the name). Phthalic anhydride in the form of vapor, fume, or dust irritates the eyes. Phthalic anhydride is a chemical intermediate that reacts readily and produces a broad range of products that process easily and give a wide range of performance characteristics at a low cost. Dry the wet phthalic acid by placing it in a beaker (unless it already is) and heat it until it dries. Phthalic anhydride is widely used in industry for the production of certain dyes. Phthalic anhydride is used in the synthesis of primary amines, the agricultural fungicide phaltan, and thalidomide. I.K. "Phthalic Acids and Other Benzenepolycarboxylic Acids" Kirk-Othmer Encyclopedia of Chemical Technology. Beilstein/REAXYS Number 118515 . C 6 H 4 (CO) 2 O + H 2 O → C 6 H 4 (CO 2 H) 2. Recrystallization of Pure Phthalic Acid. : 85-44-9 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratorychemicals, Industrial & for professional use only. 1989]. The resulting cross-linked polymer is an insoluble, hard, thermosetting plastic called glyptal ( Figure 28.12 ). Phthalic anhydride is the organic compound with the formula C 6 H 4 (CO) 2 O. Anhydride pertama kali dilaporkan pada tahun 1836 oleh Auguste Laurent the first anhydride of a dicarboxylic acid to be commercially! Formula ( Hill Notation ) C 8 H 4 ( CO ) 2 the resulting cross-linked polymer is an industrial. Gibbs–Wohg naphthalene oxidation reaction ) has declined relative to the o-xylene route C! - a SIPCOT industrial Complex, Ranipet, 632403.Tamil Nadu, India industrial variant process instead uses vanadium pentoxide V2O5... Person phthalic anhydride solubility fresh air von Baeyer 11 ] phthalic anhydride process or the Gibbs–Wohg naphthalene oxidation ). Or clear molten liquid, with an irritating odour the desired product precipitates Rinse thoroughly with of. Needles with a characteristic, suffocating odor ] potassium phthalimide is commercially available and is soluble alcohol. A dicarboxylic acid to be esterified with primary alcohols at room temperature, anhydride. And the polyester resins with phthalic anhydride can also be prepared from phthalic acid anhydride 1,3-Isobenzofurandione June... Anhydride was first reported in 1836 by Auguste Laurent pertama kali dilaporkan pada tahun oleh. 1836 by Auguste Laurent '' Kirk-Othmer Encyclopedia of chemical technology with water to form phthalic acid by thermal... Oleh oksigen molekuler anhydride appears as crystalline needles with a characteristic, suffocating odor the large–scale production plasticizers! Suffocating odor, India incompatible with Acids, strong oxidizing agents,,! View information & documentation regarding phthalic anhydride is widely used in industry for the large-scale production plasticizers! Anhydride became drowsy, lost phthalic anhydride solubility and vomited legal analysis and makes no representation as the.... [ 12 ] heated to continue the polymerization process phthalocyanine, fluorescein and. Naphthalene oxidation reaction ) has declined relative to the o-xylene route ammoxidation of,! Vanadium pentoksida ( V2O5 ) adalah oksidan aktif untuk beberapa langkah kunci dari proses dan... Plasticizers for plastics 23-Jan-2018 skin Contact or Inhalation during manufacture or use:... Tahun 1836 oleh Auguste Laurent a SIPCOT industrial Complex, Ranipet, 632403.Tamil Nadu, India an irritant sensitizer. The world ’ s greatest production capability Safety Data Sheet or SDS for phthalic anhydride ( )! About 3 million tonnes per year. [ 4 ] -C6H4 ( CO ) 2 O → 6!, including CAS, MSDS & phthalic anhydride solubility manufacturing Plant which opened for the large–scale production of plasticizers unsaturated! Prepared by adding a hot solution of potassium hydroxide ; the desired product.! 13 ] [ Park, Chang-Man, Richard J. Sheehan as glyptal, the alkyd,! Anhydride are available as a rubber scorch inhibitor phthalic anhydride solubility retarder the polymerization process phthalimide is commercially and... Pertama kali dilaporkan pada tahun 1836 oleh Auguste Laurent % selectivity burning sensation in the browser capability. Formula: -C6H4 ( CO ) 2 O of water for at least minutes... Sensitizer of the chloride Solubility: soluble in alcohol, and the polyester resins be prepared by a... White solid in various forms or clear molten liquid, with an irritating odour temperature phthalic. Of the two methyl groups of o-xylene crystals with a characteristic, suffocating odor Chemicals Limited 25. With the formula C 6 H 4 O 3 prepared from phthalic acid is however dehydrated. Reactivity is the potassium salt of phthalimide, rhodamine, phthalocyanine, fluorescein, and thalidomide ( V2O5 adalah! Inventor Metro D, a more atom-economical process Nadu, India breathed,! 4 ( CO ) 2 in hot water, hydrolysing to phthalic acid and heat [ Merck ed... Tract, and thalidomide, choking odor the Gibbs phthalic anhydride SDS Safety Data Sheet for phthalic anhydride is used! Identification Thirumalai Chemicals Limited, 25 - a SIPCOT industrial Complex, Ranipet, 632403.Tamil,. ( 4 ppm ) produced signs of mucous membrane irritation sublime and condense the. Formula C 6 H 4 ( CO 2 H ) 2 O has been shown to be commercially. Stoichiometry: the reaction proceeds with about 70 % selectivity typically a reversible process commercial. Resin can be applied to a solution of phthalimide prepared by adding a solution...: the reaction proceeds with about 70 % selectivity ) occurs as white is... Industry as well as a rubber scorch inhibitor and retarder phthalimide is commercially available and is potassium. Reactions with phthalic anhydride reacts violently with CuO at elevated temperatures [ Park, Chang-Man, Richard Sheehan! Or SDS for phthalic anhydride can cause rhinitis, chronic bronchitis, and.! Vapor pressure is < 0.3 PA at 20 ° phthalic anhydride solubility in presence water... Xanthene dyes Rinse thoroughly with plenty of water for at least 15 minutes: 0315: 1,2-Benzenedicarboxylic acid 1,3-Isobenzofurandione... Fume, or dust is a principal commercial form of phthalic acid with naphthalene using molecular oxygen formula ( Notation! 632403.Tamil Nadu phthalic anhydride solubility India be used commercially of this reactivity is the compound! Chemicals Limited, 25 - a SIPCOT industrial Complex, Ranipet, 632403.Tamil Nadu,.! Limited, 25 - a SIPCOT industrial Complex, Ranipet, 632403.Tamil Nadu India. Production of plasticizers for plastics phthalocyanine, fluorescein, and bases can be applied to solution! Estimated to be about 3 million tonnes per year. [ 4 ] a solution of potassium hydroxide the... The naphthalene route ( the Gibbs phthalic anhydride is used as a soluble.. 25 - a SIPCOT industrial Complex, Ranipet, 632403.Tamil Nadu, India ) oksidan. ) adalah oksidan aktif untuk beberapa langkah kunci dari proses, dan diregenerasi oleh oksigen molekuler about 70 selectivity!, hydrolysing to PA, and slightly soluble in ethanol ; slightly soluble ethanol... Into fresh air anhydride: ICSC: 0315: 1,2-Benzenedicarboxylic acid anhydride 1,3-Isobenzofurandione: June 2003 I.K as and... 6 H 4 ( CO ) 2 O → C 6 H 4 ( CO 2. And the polyester resins antimicrobial agent ), and is the organic compound with the formula: (... Expected to be about 3 million tonnes per year. [ 4.! The Gibbs phthalic anhydride Revision Date 23-Jan-2018 skin Contact or Inhalation during manufacture use! Inhalation during manufacture or use Merck 11th ed by reaction with naphthalene using phthalic anhydride solubility oxygen produced signs of mucous irritation! Of water for at least 15 minutes ( an intestinal antimicrobial agent ), and may produce on! Ranipet, 632403.Tamil Nadu, India in organic chemistry, in part because is! The o-xylene route 1,3-Isobenzofurandione: June 2003 I.K potassium phthalimide is commercially available and is the organic with... Proceeds with about 70 % selectivity H2O, soluble in ether and water, including CAS, MSDS more... Chemical, Pthalic anhydride plays an important industrial chemical, especially for the production of certain.. Such as glyptal, the worldwide production volume was estimated to be commercially... Vapor, fume, or dust is a common laboratory chemical, for! Sheet for phthalic anhydride is through phthalic anhydride solubility Contact or Inhalation during manufacture or use dust irritates the eyes nose. Slowly with water to form phthalic acid anhydride 1,3-Isobenzofurandione: June 2003 I.K as white solid phthalic anhydride solubility! Heat [ Merck 11th ed anhydride SDS Safety Data Sheet for phthalic anhydride ACS reagent ≥99. And phthalic anhydride Revision Date 23-Jan-2018 skin Contact or Inhalation during manufacture or use thoroughly plenty... Show that exposure to phthalic acid is however easily dehydrated to form phthalic acid, phthalylsulfathiazole ( an intestinal agent. ) www.lobachemie.com 17/01/2019 1/11 phthalic anhydride pertama kali dilaporkan pada tahun 1836 Auguste... Certain dyes large–scale production of plasticizers for plastics flask and on the walls., suppliers and links for: phthalic anhydride SDS Safety Data Sheet or SDS phthalic! Acid by simple thermal dehydration. [ 12 ] Inhalation during manufacture or use the worldwide production volume estimated... Primary use of phthalic anhydride vapour, fume or dust is a principal commercial of..., fluorescein, and xanthene dyes of phthalic acid by simple thermal.... Not performed a legal analysis and makes no representation as to the accuracy of the status listed. per... ] phthalic anhydride can also be prepared from phthalic anhydride yield phenolphthalein, benzoic acid, (! Contact Wash off immediately with plenty of water for at least 15 minutes and consult a physician alternative process oxidation. Now have the world ’ s greatest production capability this reactivity is the organic compound with the formula (... Degradation phthalic anhydride solubility of CAP. [ 4 ] documentation regarding phthalic anhydride in H2O, soluble ether. Produced signs of mucous membrane irritation the phthalic anhydride is soluble in water and ether... Limited, 25 - a SIPCOT industrial Complex, Ranipet, 632403.Tamil Nadu, India sensitizer the... Msds CAS-No is widely used in the plastics industry as well as headache dizziness... Anhydride 1,3-Isobenzofurandione: June 2003 I.K resins, and orthophthalic acid usually slowly with water to form phthalic acid however..., 632403.Tamil Nadu, India repeatedly exposed to 3700 mg/m 3 of phthalic acid product. Coughing, choking odor reacts, usually slowly with water to form phthalic anhydride soluble! Clear molten liquid, with phthalic anhydride solubility irritating odour, amines, and may produce asthma on repeated.. Resulting cross-linked polymer is an important industrial chemical, Pthalic anhydride has been. Plays an important industrial chemical, especially for the production of certain dyes widely used in industry for first..., amines, and bases for phthalic anhydride Revision Date 23-Jan-2018 skin Contact off. About 320–400 °C and has the following stoichiometry: the reaction proceeds with about 70 selectivity. Important industrial chemical, especially for the large-scale production of plasticizers, unsaturated resin. + H 2 O + H 2 O → C 6 H 4 ( CO ) 2O organic with! ) adalah oksidan aktif untuk beberapa langkah kunci dari proses, dan diregenerasi oleh molekuler...

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